2 Results for "

DIOA

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DIOA" in MCE Product Catalog:

Cat. No.: HY-137148
CAS No.: 81166-47-4
Purity:  99.1%
Target:  

Chloride Channel

Research Areas:  

Cancer

DIOA is a potent acid-sensitive outwardly rectifying (ASOR) anion channel antagonist .
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Cat. No.: HY-172533
Target:  

STING

Research Areas:  

Cancer

3’,5’-DiOA-dC is a hydrophobic nucleotide lipid and a ligand for the STING agonist c-di-GMP (CDG). 3’,5’-DiOA-dC can assemble with CDG and form stable cyclic dinucleotide nanoparticles via various supramolecular forces driven by molecular recognition. 3’,5’-DiOA-dC can decrease tumor weight and volume, increase CD8 T cell, neutrophils as well as NK cell counts in tumor microenvironment in combination with CDG. 3’,5’-DiOA-dC also increases the levels of TNF-α and IFN-γ in murine melanoma model .
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