12 Results for "

DMB

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "DMB" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W012977
CAS No.: 624-95-3
Synonyms: DMB; Neohexanol
3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine (TMA) and trimethylamine N-oxide (TMAO). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3. 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD) .
loading...
    loading...
Cat. No.: HY-W283704
CAS No.: 1425938-66-4
Target:  

Drug Intermediate

Research Areas:  

Others

Fmoc-(Dmb)Ala-OH is a peptide intermediate and can be used in peptide synthesis.
loading...
    loading...
Cat. No.: HY-116540A
CAS No.: 115116-37-5
Synonyms: 7DMB-Forskolin
Target:  

Adenylate Cyclase

Research Areas:  

Cardiovascular Disease

L 858051 (7DMB-Forskolin) dihydrochloride, an analog of Forskolin (HY-15371), is an adenylyl cyclase stimulator. L 858051 dihydrochloride directly activates adenylyl cyclase to increase intracellular, cellular, and ciliary cAMP levels. L 858051 dihydrochloride activates recombinant cyclic nucleotide-gated (E583M CNGA2) channels to induce a non-selective, Mg 2+-sensitive current in adult rat ventricular myocytes. L 858051 dihydrochloride maximally stimulates L-type Ca 2+ current in adult rat ventricular myocytes. L 858051 dihydrochloride increases total PDE3 and PDE4 activities in adult rat ventricular myocytes, with effects insensitive to PKA inhibition. L 858051 dihydrochloride serves as a tool to elevate intracellular cAMP for studying subsarcolemmal cAMP dynamics and compartmentation in adult rat ventricular myocytes .
loading...
    loading...
Cat. No.: HY-W097777
CAS No.: 119-52-8
Synonyms: 4,4'-Dimethoxybenzoin; 4,4′-DMB
Target:  

Fluorescent Dye

Research Areas:  

Others

Anisoin (4,4'-Dimethoxybenzoin) is a pre-chromatographic fluorogenic labelling reagent for (liquid chromatography) analysis of guanidino compounds (Ex/Em = 325/435 nm) .
loading...
    loading...
Cat. No.: HY-163204
Target:  

P-glycoprotein

Research Areas:  

Cancer

RhQ-DMB is a potent inhibitor of P-gp. RhQ-DMB exhibits high affinity and inhibitory activity in yeast strains expressing CmABCB1 .
loading...
    loading...
Cat. No.: HY-RS06200
Research Areas:  

Others

HLA-DMB Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DMB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-116540
CAS No.: 110452-75-0
Synonyms: 7DMB-Forskolin free base
Target:  

Adenylate Cyclase

Research Areas:  

Cardiovascular Disease

L 858051 (7DMB-Forskolin free base), an analog of Forskolin (HY-15371), is an adenylyl cyclase stimulator. L 858051 directly activates adenylyl cyclase to increase intracellular, cellular, and ciliary cAMP levels. L 858051 activates recombinant cyclic nucleotide-gated (E583M CNGA2) channels to induce a non-selective, Mg 2+-sensitive current in adult rat ventricular myocytes. L 858051 maximally stimulates L-type Ca 2+ current in adult rat ventricular myocytes. L 858051 increases total PDE3 and PDE4 activities in adult rat ventricular myocytes, with effects insensitive to PKA inhibition. L 858051 serves as a tool to elevate intracellular cAMP for studying subsarcolemmal cAMP dynamics and compartmentation in adult rat ventricular myocytes .
loading...
    loading...
Cat. No.: HY-W012977R
CAS No.: 624-95-3
Synonyms: DMB (Standard); Neohexanol (Standard)
3,3-Dimethyl-1-butanol (Standard) is the analytical standard of 3,3-Dimethyl-1-butanol (HY-W012977). This product is intended for research and analytical applications. 3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine (TMA) and trimethylamine N-oxide (TMAO). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3. 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD) .
loading...
    loading...
Cat. No.: HY-P992374
Synonyms: DMB5F3; chDMB5F3

Target:  

Mucin

Research Areas:  

Cancer

huDMB5F3 (DMB5F3; chDMB5F3) is a human monoclonal antibody against human CD227/MUC1, with a Ka value of 5.89 pM for its human target. huDMB5F3 enters MUC1-positive cancer cells via a temperature-dependent internalization process. huDMB5F3 induces cytotoxicity in MUC1-positive cancer cells. huDMB5F3 can be used in the research of various cancers including breast cancer, pancreatic cancer and gastric cancer .
loading...
    loading...
loading...
    loading...
Cat. No.: HY-P86901
Synonyms: class II antigen HLA-DM beta chain antibody; class II histocompatibility antigen antibody; Class II histocompatibility antigen M beta chain antibody; D6S221E antibody; DMB antibody; HLA class II histocompatibility antigen DM beta chain antibody; HLA-DM histocompatibility type, beta chain antibody; M beta chain antibody; Major histocompatibility complex class II DM beta antibody; MHC class II antigen DMB antibody; class II antigen HLA-DM beta chain antibody; class II histocompatibility antigen antibody; Class II histocompatibility antigen M beta chain antibody; D6S221E antibody; DMB antibody; HLA class II histocompatibility antigen DM beta chain antibody; HLA-DM histocompatibility type, beta chain antibody; M beta chain antibody; Major histocompatibility complex class II DM beta antibody; MHC class II antigen DMB antibody; MHC class II antigen HLA DM beta chain antibody; MHC class II HLA DMB antibody; OTTHUMP00000029257 antibody; Really interesting new gene 7 protein antibody; RING 7 antibody; RING7 antibody;

Host:  

Rabbit

Application:  

WB, ICC/IF, IF-Tissue, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-180820
Dimethyl bisphenolate (Compound DMB) is a natural neolignan derivative with orally active anti-tumor activity. Dimethyl bisphenolate can inhibit cancer cells proliferation, invasion and migration. Dimethyl bisphenolate can activate the p53 signaling pathway, upregulate the expression of p21 protein, inhibit the activity of the CDK1-cyclin B1 complex, and cause cells to stall at the G2/M phase. Dimethyl bisphenolate can induce ROS production, upregulate pro-apoptotic proteins Noxa and Bim, downregulate anti-apoptotic protein Bcl-2, activate caspase-9 and caspase-3, and ultimately induce cell apoptosis. Dimethyl bisphenolate can be used for research of glioblastoma .
loading...
    loading...
  • 1