1 Result for "

DMX-5804

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DMX-5804" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-111754
CAS No.: 2306178-56-1
Purity:  99.83%
Target:  

MAP4K

Research Areas:  

Cardiovascular Disease

DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice .
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