Search Result
Results for "
DOPE-PEG2000
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-144010
-
|
DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
Liposome
|
Others
|
|
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
|
-
-
- HY-N16025
-
|
|
Liposome
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG(2000) Amine ammonium is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted agent delivery and is reactive with alkyne to form a triazole ring .
|
-
-
- HY-P10392AF
-
|
|
Wnt
β-catenin
|
Cancer
|
|
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
|
-
-
- HY-W440827
-
|
|
Liposome
|
Others
|
|
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .
|
-
-
- HY-166883
-
-
-
- HY-164035
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
-
- HY-N15995
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .
|
-
-
- HY-W440995
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
-
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
-
-
- HY-160280
-
-
-
- HY-160272
-
|
|
Fluorescent Dye
|
Others
|
|
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
|
-
-
- HY-N15907
-
|
|
Liposome
|
Others
|
|
DOPE PEG(2000)-N-Cyanine 5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE PEG(2000)-N-Cyanine 5 can be used in drug delivery research.
|
-
-
- HY-166852
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
|
-
-
- HY-W591449
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
-
- HY-166846
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
|
-
-
- HY-N16036
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG(2000)-HALO-TAG ammonium is a PEG polymer containing unsaturated DOPE phospholipids. DOPE-PEG(2000)-HALO-TAG ammonium can be used to prepare liposomes or other nanoparticles for drug delivery.
|
-
-
- HY-166848
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
|
-
-
- HY-160275
-
|
|
Liposome
|
Others
|
|
DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
-
- HY-169232
-
|
|
PROTACs
|
Cancer
|
|
PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
|
-
-
- HY-W440991
-
|
DOPE-PEG2000-NH2
|
Liposome
|
Cancer
|
|
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
|
-
-
- HY-203300
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
-
- HY-P11625
-
|
|
RXFP Receptor
|
Cardiovascular Disease
|
|
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
|
-
-
- HY-P11830
-
|
|
Amylin Receptor
|
Metabolic Disease
|
|
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
|
-
-
- HY-P11596
-
|
|
Integrin
|
Cancer
|
|
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
|
-
-
- HY-P3252AS
-
|
|
Isotope-Labeled Compounds
Complement System
|
Inflammation/Immunology
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-144010
-
|
DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
|
-
- HY-166883
-
-
- HY-164035
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-160280
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 647 is a PEG-lipid-dye conjugate. composed of a DOPE phospholipid and a Fluor 647 dye .
|
-
- HY-160272
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
|
-
- HY-166852
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
|
-
- HY-166846
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
|
-
- HY-166848
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
|
-
- HY-160275
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-203300
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10392AF
-
|
|
Wnt
β-catenin
|
Cancer
|
|
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
|
-
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
-
- HY-169232
-
|
|
PROTACs
|
Cancer
|
|
PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
|
-
- HY-P11625
-
|
|
RXFP Receptor
|
Cardiovascular Disease
|
|
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
|
-
- HY-P11830
-
|
|
Amylin Receptor
|
Metabolic Disease
|
|
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
|
-
- HY-P11596
-
|
|
Integrin
|
Cancer
|
|
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
|
-
- HY-P3252AS
-
|
|
Isotope-Labeled Compounds
Complement System
|
Inflammation/Immunology
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N16025
-
|
|
Structural Classification
Lipid
|
Liposome
Biochemical Assay Reagents
|
|
DOPE-PEG(2000) Amine ammonium is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted agent delivery and is reactive with alkyne to form a triazole ring .
|
-
-
- HY-N15907
-
|
|
Structural Classification
Lipid
|
Liposome
|
|
DOPE PEG(2000)-N-Cyanine 5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE PEG(2000)-N-Cyanine 5 can be used in drug delivery research.
|
-
-
- HY-N16036
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
DOPE-PEG(2000)-HALO-TAG ammonium is a PEG polymer containing unsaturated DOPE phospholipids. DOPE-PEG(2000)-HALO-TAG ammonium can be used to prepare liposomes or other nanoparticles for drug delivery.
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-P3252AS
-
|
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-164035
-
|
|
|
DBCO
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-144010
-
|
DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
|
-
- HY-W440827
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .
|
-
- HY-166883
-
-
- HY-164035
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-N15995
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .
|
-
- HY-W440995
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
- HY-160280
-
-
- HY-160272
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
|
-
- HY-166852
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
|
-
- HY-W591449
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-166846
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
|
-
- HY-166848
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
|
-
- HY-160275
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-W440991
-
|
DOPE-PEG2000-NH2
|
|
Pegylated Lipids
|
|
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
|
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