2 Results for "

DPP-IV active site

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DPP-IV active site" in MCE Product Catalog:

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Cat. No.: HY-145779
CAS No.: 17663-87-5
Synonyms: H-γ-Glu-Met-OH; γ-Glu-Met
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

H-Glu(Met-OH)-OH (H-γ-Glu-Met-OH; γ-Glu-Met) is a DPP-IV inhibitor with an IC50 of 2.11 mM. H-Glu(Met-OH)-OH binds to DPP-IV’s active site to block substrate binding. H-Glu(Met-OH)-OH can be used for the research of type 2 diabetes .
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Cat. No.: HY-189613
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

EOS34295 is a dipeptidyl peptidase-IV (DPP-IV) inhibitor predicted to have oral activity. EOS34295 competitively binds to key residues in the active site of DPP-IV, inhibiting its enzymatic activity and blocking the degradation of incretins such as GLP-1/GIP, ultimately promoting insulin release to improve glycemic control. EOS34295 can be used in the study of type 2 diabetes .
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