2 Results for "

DPP5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DPP5" in MCE Product Catalog:

Cat. No.: HY-W035137
CAS No.: 22112-89-6
Synonyms: 5,15-DPP
Target:  

STAT

Research Areas:  

Cancer

5,15-Diphenylporphyrin (5,15-DPP) is an inhibitor of the oncogenic transcription factor STAT3. 5,15-Diphenylporphyrin specifically binds to the SH2 domain of STAT3, blocking the pTyr-SH2 interaction, thereby inhibiting the dimerization, nuclear translocation and DNA binding activity of STAT3, and ultimately inhibiting the expression of cancer cell-related genes. 5,15-Diphenylporphyrin can be used in research fields related to the development of anticancer drugs[1][2].
loading...
    loading...
Cat. No.: HY-184139
CAS No.: 3027146-73-9
Research Areas:  

Inflammation/Immunology

KGDI-109 is an orally active and selective Porphyromonas gingivalis dipeptidyl peptidase 7 (PgDPP7) inhibitor with an IC50 of 53.8 µM and a Ki of 25.1 µM. KGDI-109 is also a selective antibacterial agent that suppresses Porphyromonas gingivalis growth, reduces oral Porphyromonas gingivalis levels, and suppresses alveolar bone resorption. KGDI-109 preserves gut microbial diversity. KGDI-109 can be used for the research of periodontitis .
loading...
    loading...