2 Results for "

DVR 23

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DVR 23" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-112142
CAS No.: 1572510-80-5
Purity:  99.31%
Synonyms: (R)-DVR-23
Target:  

HBV

Research Areas:  

Infection

AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells.
loading...
    loading...
Cat. No.: HY-112142A
CAS No.: 422547-55-5
Synonyms: DVR-23
Target:  

HBV

Research Areas:  

Inflammation/Immunology

(Rac)-AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac)-AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac)-AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac)-AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model .
loading...
    loading...