2 Results for "

Difurazon

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Difurazon" in MCE Product Catalog:

Cat. No.: HY-129751
CAS No.: 2315-20-0
Synonyms: Difurazon hydrochloride
Target:  

Bacterial TrxR Apoptosis

Research Areas:  

Infection Cancer

Nitrovin hydrochloride is an antibacterial growth promoter. Nitrovin hydrochloride induces ROS-mediated non-apoptotic and apoptotic-like cell death by targeting TrxR1. Nitrovin hydrochloride has anticancer activity, with IC50 values of 1.31-6.60 μM for tumor and normal cells .
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Cat. No.: HY-W504391
CAS No.: 804-36-4
Synonyms: Difurazon
Nitrovin (Difurazon) is a thioredoxin reductase 1 (TrxR1) inhibitor with both antibacterial and anticancer activities. Nitrovin interacts with TrxR1 to generate reactive oxygen species (ROS), which in turn induces cytoplasmic vacuolization, activates MAPK and inhibits Alix. Nitrovin induces paraptosis-like non-apoptotic cell death, thereby exerting significant cytotoxicity against cancer cells. Nitrovin can be used in the research of heart disease and glioblastoma multiforme .
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