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Dipsacus asper

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By Targets:	Akt (2) Apoptosis (2) Caspase (2) Drug Derivative (2) Fungal (1) HIF/HIF Prolyl-Hydroxylase (2) p38 MAPK (2) PERK (2) PPAR (2) Reference Standards (1)
By Research Areas:	Cardiovascular Disease (2) Infection (2) Metabolic Disease (1) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0265

Asperosaponin VI 3 Publications Verification Akebia saponin D	Caspase Apoptosis PERK p38 MAPK Akt HIF/HIF Prolyl-Hydroxylase PPAR	Cardiovascular Disease Neurological Disease
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

HY-N3557

Cauloside A Leontoside A	Fungal	Infection
Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity .

HY-N15723

Dipsacus saponin A	Others	Others
Dipsacus saponin A is an orally active triterpenoid saponin found in the roots of Dipsacus asper. Dipsacus saponin A promotes bone repair by regulating osteoblast activity and inhibiting osteoclast function. Dipsacus saponin A is promising for research of bone diseases such as fracture healing and osteoporosis .

HY-N2238

Dipsanoside A	Others	Metabolic Disease
Dipsanoside A is a novel tetrairidoid glucoside from Dipsacus asper. Dipsacus asper Wall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissiparism promoter of the osseous cells, and as an embryo security agent, etc .

HY-N9352

Cantleyoside	Others	Others
Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper .

HY-N2236

Dipsanoside B	Others	Infection
Dipsanoside B is a novel tetrairidoid glucoside from Dipsacus asper. Dipasandin B shows s an anti-osteoarthritis effect. Dipsacus asper Wall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissiparism promoter of the osseous cells, and as an embryo security agent, etc .

HY-N0265R

Asperosaponin VI (Standard) Akebia saponin D (Standard)	Reference Standards Caspase Apoptosis PERK Akt p38 MAPK HIF/HIF Prolyl-Hydroxylase PPAR	Cardiovascular Disease Neurological Disease
Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

HY-N17309

3'-O-Acetyl-akebia saponin D	Drug Derivative	Others
3'-O-Acetyl-akebia saponin D (compound 23) is a triterpenoid saponin found in the roots of Dipsacus asper (Radix Dipsaci).3'-O-Acetyl-akebia saponin D is an isomer of 4'-O-acetyl-akebia saponin D .

HY-N17570

23α-Hydroxy-olean-12-en-3-one	Drug Derivative	Others
23α-Hydroxy-olean-12-en-3-one (Compound 15) is a pentacyclic triterpenoid, which is a natural derivative of the oleanane skeleton .

Asperosaponin VI 3 Publications Verification Akebia saponin D	Cardiovascular Disease Triterpenes Structural Classification Classification of Application Fields Terpenoids Dipsacaceae Dipsacus asper Wall. Plants Disease Research Fields Source Classification	Caspase Apoptosis PERK p38 MAPK Akt HIF/HIF Prolyl-Hydroxylase PPAR
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

Cauloside A Leontoside A	Infection Triterpenes Classification of Application Fields Terpenoids Dipsacaceae Dipsacus asper Wall. Plants Disease Research Fields Source Classification	Fungal
Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity .

Dipsacus saponin A	Triterpenes Terpenoids Dipsacaceae Dipsacus asper Wall. Plants Source Classification	Others
Dipsacus saponin A is an orally active triterpenoid saponin found in the roots of Dipsacus asper. Dipsacus saponin A promotes bone repair by regulating osteoblast activity and inhibiting osteoclast function. Dipsacus saponin A is promising for research of bone diseases such as fracture healing and osteoporosis .

Dipsanoside A	Iridoids Classification of Application Fields Terpenoids Dipsacaceae Metabolic Disease Dipsacus asper Wall. Plants Disease Research Fields Source Classification	Others
Dipsanoside A is a novel tetrairidoid glucoside from Dipsacus asper. Dipsacus asper Wall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissiparism promoter of the osseous cells, and as an embryo security agent, etc .

Cantleyoside	Iridoids Classification of Application Fields Terpenoids Dipsacaceae Other Diseases Dipsacus asper Wall. Plants Disease Research Fields Source Classification	Others
Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper .

Dipsanoside B	Infection Structural Classification Iridoids Classification of Application Fields Terpenoids Dipsacaceae Dipsacus asper Wall. Plants Disease Research Fields Source Classification	Others
Dipsanoside B is a novel tetrairidoid glucoside from Dipsacus asper. Dipasandin B shows s an anti-osteoarthritis effect. Dipsacus asper Wall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissiparism promoter of the osseous cells, and as an embryo security agent, etc .

Asperosaponin VI (Standard) Akebia saponin D (Standard)	Triterpenes Structural Classification Terpenoids Dipsacaceae Dipsacus asper Wall. Plants Source Classification	Reference Standards Caspase Apoptosis PERK Akt p38 MAPK HIF/HIF Prolyl-Hydroxylase PPAR
Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .

3'-O-Acetyl-akebia saponin D	Structural Classification Polysaccharides Caprifoliaceae Dipsacus asper Wall. Plants Saccharides Source Classification	Drug Derivative
3'-O-Acetyl-akebia saponin D (compound 23) is a triterpenoid saponin found in the roots of Dipsacus asper (Radix Dipsaci).3'-O-Acetyl-akebia saponin D is an isomer of 4'-O-acetyl-akebia saponin D .

23α-Hydroxy-olean-12-en-3-one	Triterpenes Structural Classification Caprifoliaceae Terpenoids Dipsacus asper Wall. Plants Source Classification	Drug Derivative
23α-Hydroxy-olean-12-en-3-one (Compound 15) is a pentacyclic triterpenoid, which is a natural derivative of the oleanane skeleton .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Dipsacus asper

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