42 Results for "

Drosophila melanogaster

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "Drosophila melanogaster" in MCE Product Catalog:

316
316 Publications Verification
Cat. No.: HY-15452
CAS No.: 49843-98-3
Purity:  99.85%
Synonyms: EX-527
Target:  

Sirtuin

Research Areas:  

Inflammation/Immunology Cancer

Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease .
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39
39 Cited Publications
Cat. No.: HY-100168
CAS No.: 85233-19-8
Purity:  98.10%
BAPTA is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
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39
39 Cited Publications
Cat. No.: HY-100168A
CAS No.: 126824-24-6
Purity:  99.70%
Target:  

Phospholipase

Research Areas:  

Others

BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
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39
39 Cited Publications
Cat. No.: HY-100168B
CAS No.: 73630-08-7
Purity:  99.45%
BAPTA tetrapotassium is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
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2
2 Cited Publications
Cat. No.: HY-112820
CAS No.: 500008-45-7
Purity:  98.06%
Research Areas:  

Others

Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ~300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
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1
1 Cited Publications
Cat. No.: HY-116564
CAS No.: 1369852-71-0
Purity:  99.84%
Target:  

Parasite GABA Receptor

Research Areas:  

Infection

Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor .
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1
1 Cited Publications
Cat. No.: HY-N6689
CAS No.: 6686-70-0
Destruxin A is a fungal cyclopeptide with insecticidal and antiviral activities. Destruxin A has a certain inhibitory effect on leukemia cells in vitro. Destruxin A can also specifically inhibit the innate immune response of Drosophila melanogaster, making the flies more susceptible to bacterial infections .
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Cat. No.: HY-N13250
Hawthorn Extract is an orally active hawthorn extract. Hawthorn Extract decreases Bax expression and increases Bcl-2 expression in the aorta. Hawthorn Extract regulates the AMPK signaling pathway, induces apoptosis, enhances the hepatic antioxidant system, and ameliorates symptoms of liver injury, inflammation and cancer. Hawthorn Extract reduces plasma levels of pro-inflammatory factors, increases plasma levels of anti-inflammatory adiponectin, and alleviates atherosclerotic plaque lesions in the aorta. Hawthorn Extract improves symptoms associated with chronic heart failure . Hawthorn Extract inhibits FMLP-induced superoxide anion production, Elastase release, ILB4 generation and calcium signaling in neutrophils, and also reduces LPS-induced cytokine production in neutrophils. Hawthorn Extract induces autophagy and inhibits the proliferation of intestinal stem cells. Hawthorn Extract can be used in research related to atherosclerosis, hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, hepatocellular carcinoma, chronic heart failure and hypotension .
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Cat. No.: HY-W134423A
CAS No.: 9002-18-0
Agar, microbiology tested, for cell culture (granular) is a hydrocolloid with gelling ability. Agar, microbiology tested, for cell culture (granular) can be used to prepare microbial culture media (for bacteria, yeasts and molds) .
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Cat. No.: HY-139440
CAS No.: 56217-82-4
Purity:  99.54%
Research Areas:  

Others

DL-Leucyl-DL-phenylalanine is a dipeptide and can be used as a substrate to detecte two regions of dipeptidase staining on a gel in Drosophila simulans as well as in Drosophila melanogaster .
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Cat. No.: HY-15452R
CAS No.: 49843-98-3
Synonyms: EX-527 (Standard)
Research Areas:  

Inflammation/Immunology Cancer

Selisistat (Standard) is the analytical standard of Selisistat. This product is intended for research and analytical applications. Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease .
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Cat. No.: HY-113401
CAS No.: 634-01-5
Target:  

Endogenous Metabolite

Research Areas:  

Others

Adenosine 2',3'-cyclic phosphate is a naturally occurring adenosine cyclic phosphate derivative. Adenosine 2',3'-cyclic phosphate is used to detect the activity of 2',3'-cyclic nucleotide 3'-phosphodiesterase .
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Cat. No.: HY-Y1668
CAS No.: 630-19-3
Synonyms: Pivalic aldehyde; Pivalaldehyde
Research Areas:  

Others

Trimethylacetaldehyde (Pivalic aldehyde; Pivalaldehyde) is an inhibitor of E. coli betaine aldehyde dehydrogenase (ALDH) with a Ki of 4.5 mM. Trimethylacetaldehyde serves as a substrate for Drosophila melanogaster alcohol dehydrogenase (AdhS), undergoing oxidation and disproportionation reactions with the release of NADH, and also forms an inactive binary enzyme-aldehyde complex via a compulsory ordered reaction mechanism .
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Cat. No.: HY-D0121
CAS No.: 96314-96-4
INDO 1 is a cell-impermeable, dual-emission ratiometric fluorescent calcium indicator with a KD·β value of 0.44 μM. INDO 1 binds to intracellular free calcium ions and undergoes wavelength-dependent fluorescence changes. In the unbound state (free form) without Ca 2+, its fluorescence emission peak is at 485 nm upon excitation with ultraviolet light (350 nm). When INDO 1 pentasodium binds to Ca 2+ (bound state), the emission peak shifts to 405 nm (Ex = 350 nm; dual emission at Em= 405/485 nm) .
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Cat. No.: HY-P11380
CAS No.: 454186-80-2
Capa-2 is a neuropeptide. Capa-2 activates calcium ion influx, stimulates the production of NO, activates soluble guanylate cyclase (sGC), increases intracellular cGMP, and drives ion and fluid secretion. Capa-2 can be used in studies of diuresis .
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Cat. No.: HY-W009165R
CAS No.: 27519-02-4
Synonyms: cis-9-Tricosene (Standard)
(Z)-9-Tricosene (Standard) (cis-9-Tricosene (Standard)) is the analytical standard of (Z)-9-Tricosene (HY-W009165). This product is intended for research and analytical applications. (Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone found in dipteran flies. (Z)-9-Tricosene has multiple functions as a sex pheromone, aggregation pheromone and aphrodisiac pheromone, and mediates insect behaviors such as attraction, oviposition and mating via antennal receptors (e.g., the Or7a receptor). (Z)-9-Tricosene can be used in studies related to insecticides and insect chemical ecology .
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Cat. No.: HY-P5719
Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .
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Cat. No.: HY-P5444
CAS No.: 149924-99-2
Target:  

Bacterial

Research Areas:  

Others

Drosocin is a biological active peptide. (Drosocin is a 19-mer cationic antimicrobial peptide from Drosophila melanogaster. In Drosophila native drosocin carries a disaccharide moiety attached to a threonine residue in mid-chain position. This synthetic drosocin peptide of identical amino acid sequence without the disaccharide has an activity several times lower than the native compound.)
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Cat. No.: HY-112820R
CAS No.: 500008-45-7
Research Areas:  

Others

Chlorantraniliprole (Standard) is the analytical standard of Chlorantraniliprole. This product is intended for research and analytical applications. Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ~300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
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Cat. No.: HY-W009165
CAS No.: 27519-02-4
Synonyms: cis-9-Tricosene
Target:  

Insecticide

(Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone found in dipteran flies. (Z)-9-Tricosene has multiple functions as a sex pheromone, aggregation pheromone and aphrodisiac pheromone, and mediates insect behaviors such as attraction, oviposition and mating via antennal receptors (e.g., the Or7a receptor). (Z)-9-Tricosene can be used in studies related to insecticides and insect chemical ecology .
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