3 Results for "

EMD 1214063

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "EMD 1214063" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-14721
CAS No.: 1100598-32-0
Purity:  99.94%
Synonyms: EMD-1214063
Target:  

c-Met/HGFR Autophagy

Research Areas:  

Cancer

Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
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Cat. No.: HY-14721R
CAS No.: 1100598-32-0
Synonyms: EMD-1214063 (Standard)
Research Areas:  

Cancer

Tepotinib (Standard) is the analytical standard of Tepotinib. This product is intended for research and analytical applications. Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation. Tepotinib has antitumor effects .
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Cat. No.: HY-14721A
CAS No.: 1103508-80-0
Synonyms: EMD-1214063 hydrochloride
Target:  

c-Met/HGFR Autophagy

Research Areas:  

Cancer

Tepotinib (EMD-1214063) hydrochloride is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib hydrochloride inhibits c-Met phosphorylation and induces autophagy. Tepotinib hydrochloride has antitumor effects .
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