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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
EX1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "EX1" in MCE Product Catalog:
Synonyms: ARO-AAT sodium
Target:
Forschungsgebiete:
Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes [1]. Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. AATD is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Art. -Nr.: HY-132604
CAS. Nr.: 2175009-08-0
Synonyms: ARO-AAT
Target:
Forschungsgebiete:
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively reduce Alpha1-antitrypsin (AAT) synthesis and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes [1]. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. Alpha-1 antitrypsin deficiency (AATD) is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Art. -Nr.: HY-173324
CAS. Nr.: 3070072-52-2
Target:
Forschungsgebiete:
LPA2 antagonist 5 (EX1) is a LPA2 antagonist, with an IC50 of 4.05 nM [1].
Art. -Nr.: HY-172129
CAS. Nr.: 2636786-68-8
Target:
Forschungsgebiete:
HDAC6-IN-52 (EX.1) is a potent inhibitor of HDAC6, with the inhibitory rate of 100% at 10 μM. HDAC6-IN-52 plays an important role in central nervous system diseases including neurodegenerative diseases such as Alzheimer’s disease andprogressive supranuclear palsy [1].
Art. -Nr.: HY-RS05104
Target:
Forschungsgebiete:
FRMD6 Human Pre-designed siRNA Set A contains three designed siRNAs for FRMD6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-185177
CAS. Nr.: 2446126-42-5
Antifungal agent 156 (Ex.1-123) is a heterocyclic pyridazine compound and a phytopathogenic fungal control agent, which can be used in studies related to phytopathogenic fungal infection [1].
Art. -Nr.: HY-177410
CAS. Nr.: 1803346-97-5
Target:
Forschungsgebiete:
Muscarinic M1 receptor agonist-1 (Ex.1-21) is a Muscarinic M1 receptor agonist. Muscarinic M1 receptor agonist-1 can be used in the research of psychiatric disorders such as schizophrenia [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
