2 Results for "

FEV1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "FEV1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-108858
CAS No.: 143831-71-4
Synonyms: rhDNase
Research Areas:  

Inflammation/Immunology

Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms [1] .
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Cat. No.: HY-P992359
Synonyms: SHR-1905

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

GSK5784283 (SHR-1905) is a bivalent antibody against TSLP, which is applicable to research related to asthma. GSK5784283 has two Fab arms and is a humanized IgG1κ monoclonal antibody. GSK5784283 effectively reduces the levels of eosinophils, FeNO, TARC and eotaxin-3. GSK5784283 regulates FEV1 (forced expiratory volume in one second) [1].
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