2 Results for "

FOG001

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "FOG001" in MCE Product Catalog:

Cat. No.: HY-P10925
CAS No.: 3044032-95-0
Synonyms: FOG-001; I-66
Target:  

β-catenin

Research Areas:  

Cancer

Zolucatetide (FOG-001;I-66) is a potent β-catenin inhibitor with an IC50 of <50 nM. Zolucatetide can inhibits β-catenin and T-cell factor (TCF) transcription factor interaction. Zolucatetide inhibits cell proliferation and induces cell cycle arrest in target cells. Zolucatetide exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell (with APC, TP53 mutations) xenografts. Zolucatetide can be used for the study of colon cancer .
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Cat. No.: HY-P10925A
Synonyms: (Z)-FOG-001; I-67
Target:  

β-catenin

Research Areas:  

Cancer

(Z)-Zolucatetide (I-67) is a β-catenin inhibitor with IC50 ≤50 nM. (Z)-Zolucatetide's sequence is Ac-PL3-Asp-Npg-B5-Asp-3COOHF-Aib-Ala-Phe-Lys3-PyrS2-3Thi-BztA-GlnR3-Ala-NH2. (Z)-Zolucatetide can be used for cancer research .
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