1 Result for "

FORX864

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FORX864" in MCE Product Catalog:

Cat. No.: HY-190864
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

FORX-864 is an irreversible covalent inhibitor of RAD52. FORX-864 covalently modifies adjacent cysteines and occupies the ssDNA-binding groove, blocking ssDNA binding. FORX-864 has a target IC50 of 5 nM and 7 nM for human RAD52. FORX-864 inhibits RAD52-dependent single-strand annealing in cells without cytotoxicity and lacks activity in RAD52 knockout cells. FORX-864 can be used for research related to RAD52-mediated diseases .
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