8 Results for "

FRET-based

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "FRET-based" in MCE Product Catalog:

Cat. No.: HY-P1859
CAS No.: 438625-61-7
Target:  

Fluorescent Dye

Research Areas:  

Others

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
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Cat. No.: HY-P11302
Target:  

CHIKV Virus Protease

Research Areas:  

Infection

DABCYL-RAGGYIFS-(E-EDANS)-NH2, an octapeptide, is a FRET-based substrate peptide of CHIKV nsP2protease with highly sensitivity. DABCYL-RAGGYIFS-(E-EDANS)-NH2 can be cleaved by the active CHIKV nsP2protease, separating fluorophore and quencher and resulting in an increase of fluorescence signal. DABCYL-RAGGYIFS-(E-EDANS)-NH2 can used for the determination of CHIKV nsP2protease activity .
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Cat. No.: HY-D1079
CAS No.: 100900-07-0
Target:  

DNA Stain

Research Areas:  

Others

EDANS sodium is a potent fluorogenic substrates. EDANS sodium is a donor for FRET-based nucleic acid probes and protease substrates. EDANS sodium is often paired with DABCYL or DABSYL. The optimal absorbance and emission wavelengths of EDANS sodium are λabs = 336 nm and λem = 490 nm respectively .
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Cat. No.: HY-P5415
CAS No.: 127134-13-8
Target:  

HIV

Research Areas:  

Others

DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-Kd protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
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Cat. No.: HY-P1859A
Research Areas:  

Others

MCA-SEVNLDAEFR-K(Dnp)-RR, amide (acetate) is synthesized from MCA-SEVNLDAEFR-K(Dnp)-RR, amide (HY-P1859) by losing the H of the -OH group of acetic acid. MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
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Cat. No.: HY-D3406
Dusquench3 azide is a non-fluorescent dark quencher that absorbs emission from a nearby fluorophore without generating a fluorescent signal of its own. It contains an azide group, making it suitable for click chemistry reactions (CuAAC). Dusquench3 azide is primarily used in FRET-based nucleic acid probes, molecular beacons, and multiplex qPCR assays.
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Cat. No.: HY-D3407
Dusquench2 dT phosphoramidite is a non-fluorescent dark quencher that absorbs emission from nearby fluorophores without generating its own fluorescent signal. Featuring a dT phosphoramidite moiety, it is designed for incorporation during oligonucleotide synthesis. Dusquench2 dT phosphoramidite is primarily used in FRET-based nucleic acid probes, molecular beacons, and multiplex qPCR assays.
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Cat. No.: HY-W1058961
CAS No.: 1401661-20-8
Target:  

ROCK

Research Areas:  

Others

4-(Indolin-1-yl) pyrimidin-2-amine (13a, non-salt form) is a ROCK inhibitor .
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