1 Result for "

FRT cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FRT cells" in MCE Product Catalog:

Cat. No.: HY-123967
CAS No.: 324579-65-9
Purity:  99.91%
Research Areas:  

Inflammation/Immunology

RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 rescues F508del-CFTR function in F508del-CFTR-expressing immortalized cells (CFBE41o⁻, EC50 = 2.6 μM; FRT, EC 50 = 2.2 μM). RNF5 inhibitor inh-02 increases LC3IIB expression and autophagic vacuole number via reducing ATG4B ubiquitylation and promotes cell motility. RNF5 inhibitor inh-02 can be used for the study of cystic fibrosis .
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