6 Results for "

FVB mice

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "FVB mice" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-125527A
CAS. Nr.: 528583-91-7
Reinheit:  99.1%
Synonyms: 17(R)-RvD1; AT-RvD1
Target:  

TRP Channel

Forschungsgebiete:  

Inflammation/Immunology

17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy .
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Art. -Nr.: HY-P10641
CAS. Nr.: 876460-72-9
Target:  

Exosomes STAT ERK Akt

Forschungsgebiete:  

Cardiovascular Disease

Heart-homing peptide is a heart-targeting peptide with the sequence CRPPR that mediates cardiac endothelial targeting and accumulates in cardiac tissues. Heart-homing peptide mediates the translocation of liposomal and exosomal cargos across cardiac endothelium into interstitial tissues, enhances the accumulation of exosomes in the heart, and inhibits the GP130-STAT3/ERK1/2/AKT pathway. Heart-homing peptide accumulates at sites of ischemia/reperfusion, myocardial infarction and hypertrophy in mice. Heart-homing peptide can be used for the research of cardiovascular diseases .
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Art. -Nr.: HY-125516
CAS. Nr.: 1784701-63-8
Reinheit:  98.40%
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Others Inflammation/Immunology

MCTR3 is a potent cytokine of pro-resolving mediating maresin conjugates in tissue regeneration (MCTR), which reduces the inflammatory response and promotes the tissue regeneration. MCTR3 exhibits potency in ameliorating LPS-induced acute lung injury and arthritis .
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Art. -Nr.: HY-178045
CAS. Nr.: 3109265-41-7
Target:  

c-Myc

Forschungsgebiete:  

Cancer

MYC-IN-4 is a MYC inhibitor. MYC-IN-4 impairs MYC/MAX protein-protein interaction (IC50 = 3.06 μM). MYC-IN-4 inhibits MYC-aberrant PC-3 prostate cancer cells with an IC50 of 0.440 μM. MYC-IN-4 demonstrates potent antitumor efficacy in FVB mice bearing Myc-CaP prostate tumor allografts. MYC-IN-4 can be used for the study of prostate cancer .
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Art. -Nr.: HY-P11028
Target:  

CDK

Forschungsgebiete:  

Cancer

M1-20 is a CDK1 inhibitor. M1-20 promotes CDK1 ubiquitination by CUL4-DDB1-DCAF1 complexes and degradation through the proteasome pathway. M1-20 abolishes the formation of CDK1/CCNB1 complexes. M1-20 has significant anticancer activity of spontaneous breast cancer in FVB/N MMTV-PyVT mice model .
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Art. -Nr.: HY-P991966

Target:  

EGFR

Forschungsgebiete:  

Cancer

Anti-Human/Mouse EGFR Antibody (7A7) ia an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Anti-Human/Mouse EGFR Antibody (7A7) fails to induce tumor regression in the HPV38 tumor model where EGFR is not expressed in mice. Anti-Human/Mouse EGFR Antibody (7A7) can be used in EGFR-expressing HPV38 tumor-related studies .
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