Fe dextran

Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals .

The core material of carboxylated dextran-modified iron oxide nanoparticles is iron oxide (Fe₃O₄), which possesses superparamagnetic properties, making it suitable for applications requiring magnetic field response. The surface is coated with carboxylated dextran, a modification that increases the nanoparticles' water solubility and biocompatibility, while also providing carboxyl functional groups, facilitating further chemical modification and biomolecular coupling.

Carboxymethyl dextran-modified iron(III) oxide nanoparticles are composite materials in which carboxymethyl dextran (CMD) is introduced onto the surface of iron(III) oxide (Fe₃O₄) nanoparticles through chemical modification. Carboxymethyl dextran is a water-soluble polysaccharide; its hydrophilicity and biocompatibility are enhanced by converting the hydroxyl groups of the dextran into carboxymethyl groups (-COOH).

Ferric oxide (Fe₃O₄) is widely used in magnetic resonance imaging (MRI), magnetic separation, targeted drug delivery, tumor hyperthermia, cell labeling and separation, and as a contrast agent and enhancement agent in retinal detachment repair surgery due to its stable material properties, good biocompatibility, high strength, and lack of toxic side effects. It is also used as a catalyst carrier, microwave absorbing material, and magnetic recording material. Xianfeng has developed numerous derivatives of ferric oxide, including oleic acid-modified ferric oxide, PEG-terminated ferric oxide, DMSA-modified ferric oxide, polylysine-modified ferric oxide, carboxylated dextran-modified ferric oxide nanoparticles, streptavidin-modified ferric oxide particles, thiol-modified ferric oxide magnetic nanoparticles, and polyethyleneimine (PEI)-modified magnetic ferric oxide nanoparticles, among others. This wide range of modifications provides numerous options for subsequent experiments.