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Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals.

For research use only. We do not sell to patients.

Iron dextran Chemical Structure

Iron dextran Chemical Structure

CAS No. : 9004-66-4

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Based on 1 publication(s) in Google Scholar

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Description

Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals[1][2].

In Vivo

Iron dextran (FeDex, IP, 4 weeks, 300 μL of 10 mg) treatment does not increase NSR iron but causes iron-trapping in the tetinal vasculature[1].
Four weeks of IP FeDex injection in 2-month-old WT mice leads to iron accumulation in the RPE and rVECs, but did not increase NSR iron or induce photoreceptor degeneration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild-type (WT) and RS-HepcKO mice[1].
Dosage: IP.
Administration: 300 μL of 10 mg daily for 5 days each week for 2 or 4 weeks.
Result: Markedly elevated iron levels in 2 and 4 weeks of FeDex-injection groups, by 365.4-fold and 405.4-fold, respectively, compared with PBS controls.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Brown to reddish brown

SMILES

[Iron dextran]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL

*"≥" means soluble, but saturation unknown.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

COA (242 KB)

Handling Instructions (2659 KB)
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Iron dextran Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Iron dextran9004-66-4Fe dextranOthersInhibitorinhibitorinhibit

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Iron dextran
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HY-107928
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