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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Fibroblast growth factor receptor 4
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Fibroblast growth factor receptor 4" in MCE Product Catalog:
11
11 Cited Publications
BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity .
5
Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling .
Cat. No.: HY-174687
Human FGFR4 mRNA encodes the human fibroblast growth factor receptor 4 (FGFR4) protein, a tyrosine kinase and cell surface receptor for fibroblast growth factors. FGFR4 is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis.
Cat. No.: HY-159691
CAS No.: 1416376-17-4
Synonyms: ISIS 463588
Target:
Research Areas:
IONIS-FGFR4Rx (ISIS 463588) is an antisense inhibitor of fibroblast growth factor receptor 4 (FGFR4), which is promising for research of renal diseases .
Cat. No.: HY-159691A
Synonyms: ISIS 463588 sodium
Target:
Research Areas:
IONIS-FGFR4Rx (ISIS 463588) sodium is an antisense inhibitor of fibroblast growth factor receptor 4 (FGFR4), which is promising for research of renal diseases .
Cat. No.: HY-158248
CAS No.: 3036751-84-2
FGFR4-IN-19 (compound 8B) is a potent covalent fibroblast growth factor receptor 4 (FGFR4) inhibitor (IC50=1.2 nM). FGFR4-IN-19 achieves high efficiency and isotype selectivity by covalently targeting a rare cysteine (C552) in the FGFR4 kinase domain. FGFR4-IN-19 can be used for hepatocellular carcinoma (HCC) research .
Cat. No.: HY-P73061
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor receptor; CD334 Antigen; Fibroblast growth factor receptor; FGFR-4
Species:
Rat
Source:
HEK293
Cat. No.: HY-P706055
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor receptor; CD334 Antigen; Fibroblast growth factor receptor; FGFR-4
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706056
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor receptor; CD334 Antigen; Fibroblast growth factor receptor; FGFR-4
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P73057
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Human
Source:
HEK293
Cat. No.: HY-P73059
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Human
Source:
HEK293
Cat. No.: HY-P75191
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76929
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P73061A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Rat
Source:
HEK293
Cat. No.: HY-P702761
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P73060
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75190
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76928
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; receptor Protein-Tyrosine Kinase; Fibroblast growth factor receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast growth factor Recept
Species:
Rhesus Macaque
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
