1 Result for "

GDC0853

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GDC0853" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-19834
CAS No.: 1434048-34-6
Synonyms: GDC-0853
Target:  

Btk

Research Areas:  

Cancer

Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research .
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