1 Result for "

GQ16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GQ16" in MCE Product Catalog:

Cat. No.: HY-111254
CAS No.: 870554-67-9
Purity:  98.88%
Target:  

PPAR NF-κB JNK

Research Areas:  

Inflammation/Immunology

GQ-16 is an orally active PPARγ partial agonist with an IC50 of 1.84 μM and a Ki of 160 nM against human PPARγ. GQ-16 inhibits Cdk5-mediated Ser-273 phosphorylation. GQ-16 improves insulin sensitivity and glucose tolerance in obese and diabetic mice. GQ-16 also exhibits certain cytotoxicity against tumor cells. GQ-16 can be used in research related to obesity, diabetes and cancer .
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