1 Result for "

GS143

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GS143" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-110261
CAS No.: 916232-21-8
Purity:  99.09%
Target:  

IKK E1/E2/E3 Enzyme NF-κB

Research Areas:  

Inflammation/Immunology

GS143 is a selec­tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCF βTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB acti­va­tion and tran­scrip­tion of tar­get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect .
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