1 Result for "

GS1811

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GS1811" in MCE Product Catalog:

Cat. No.: HY-P990914
CAS No.: 2865822-82-6
Synonyms: GS-1811; JTX-1811

Target:  

CCR

Research Areas:  

Inflammation/Immunology Cancer

Denikitug (GS-1811; JTX-1811) is a humanized monoclonal antibody against CCR8 receptor with a KD of 16.8 pM. Denikitug specifically binds to human CCR8, inhibits CCL1-induced downstream CCR8 signaling. Denikitug selectively depletes cells expressing CCR8 via antibody-dependent cellular cytotoxicity (ADCC). Denikitug promotes anti-tumor immunity and can be used for the research of cancer and immunology .
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