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Results for "

Guanosine 5'-triphosphate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (1) Arf Family GTPase (1) DNA/RNA Synthesis (7) Drug Derivative (3) Drug Isomer (1) Endogenous Metabolite (14) Exosomes (3) Fluorescent Dye (2) GLUT (2) Glutamate Dehydrogenase (GLDH) (1) Guanylate Cyclase (1) Hepcidin (5) Interleukin Related (2) Isotope-Labeled Compounds (7) MicroRNA (1) Nucleoside Antimetabolite/Analog (5) P2X Receptor (1) Potassium Channel (9) Reference Standards (1) STAT (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (1) Infection (3) Inflammation/Immunology (10) Metabolic Disease (9) Neurological Disease (3)
Oligonucleotides:	Guanine Nucleotide (3) Guanosine (1) Nucleoside Analogs (2) Nucleotide Analogs (11) Cap Analogs (3) Adenine Nucleotide (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: NTPDase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010737

Guanosine-5'-triphosphate disodium salt Maximum Cited Publications 8 Publications Verification 5'-GTP disodium salt	Exosomes Endogenous Metabolite MicroRNA	Metabolic Disease
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-12695

Guanosine 5'-triphosphate trisodium 5 Publications Verification 5'-GTP trisodium	Exosomes Endogenous Metabolite DNA/RNA Synthesis	Metabolic Disease
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate trisodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt	Hepcidin Potassium Channel Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-113066C

Guanosine 5'-diphosphate sodium, 96% (HPLC) 2 Publications Verification GDP sodium, Type I, 96% (HPLC)	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-137677B

GTPγS tetralithium Guanosine 5'-[γ-thio]triphosphate tetralithium	GLUT	Metabolic Disease
GTPγS (Guanosine 5'-[γ-thio]triphosphate) tetralithium is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS tetralithium to couple with G- protein α, to study its effect on kinase activity. GTPγS tetralithium acts as a component of lysis buffer .

HY-12695B

Guanosine 5'-triphosphate trisodium salt hydrate Maximum Cited Publications 8 Publications Verification 5'-GTP trisodium salt hydrate	Exosomes Endogenous Metabolite DNA/RNA Synthesis	Metabolic Disease
Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-100767

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Adenylate Cyclase	Endocrinology
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

HY-113066

Guanosine 5'-diphosphate GDP	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-21586B

*7-Methyl-guanosine-5'-triphosphate* sodium** m7GTP sodium	Nucleoside Antimetabolite/Analog	Others
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-139100B

m7G(5')ppp(5')A diammonium m7GpppA diammonium; N7-Methyl-Guanosine-5'-triphosphate-5'-adenosine diammonium	DNA/RNA Synthesis	Infection
m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-139101A

Guanosine 5'-triphosphate-5'-adenosine triammonium GpppA triammonium	DNA/RNA Synthesis Endogenous Metabolite	Others
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium GDP-13C10 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-150768S

Guanosine 5'-triphosphate (GTP), ammonium salt-d27	Isotope-Labeled Compounds	Others
Guanosine 5'-triphosphate (GTP), ammonium salt-d₂₇ is the deuterium labeled Guanosine 5'-triphosphate (GTP), ammonium salt .

HY-150773S

Guanosine 5'-triphosphate(GTP)-d4 ammonium salt	Isotope-Labeled Compounds	Others
Guanosine 5'-triphosphate(GTP)-d₄ (ammonium salt) is the deuterium labeled Guanosine 5'-triphosphate(GTP) ammonium salt .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA	DNA/RNA Synthesis Endogenous Metabolite	Others
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-139100

*N7-Methyl-guanosine-5'-triphosphate-5'-adenosine* m7GpppA	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium GDP-15N5 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113066AR

Guanosine 5'-diphosphate disodium salt (Standard) GDP disodium salt (Standard)	Hepcidin Endogenous Metabolite Potassium Channel Reference Standards	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-150796S

Guanosine 5'-triphosphate, ammonium salt-15N5	Isotope-Labeled Compounds	Others
Guanosine 5'-triphosphate, ammonium salt- ¹⁵N₅ is the ¹⁵N labeled Guanosine 5'-triphosphate, ammonium salt .

HY-21586

*7-Methyl-guanosine-5'-triphosphate* disodium** m7GTP disodium	Nucleoside Antimetabolite/Analog	Metabolic Disease
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-154121

*2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate* ammonium**	Nucleoside Antimetabolite/Analog	Cancer
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-173535

TNP-β-L-GTP tetrasodium TNP-β-L-Guanosine 5'-triphosphate tetrasodium	Arf Family GTPase	Others
TNP-β-L-GTP (TNP-β-L-Guanosine 5'-triphosphate) tetrasodium is a fluorescent GTP mimetic that can be used to study the binding kinetics and affinity of GTP-binding proteins (such as G proteins and GTPases). TNP-β-L-GTP tetrasodium carries a TNP fluorophore, which changes fluorescence intensity upon protein binding, allowing for quantitative analysis .

HY-173530

8-Bromo TNP-GTP tetrasodium 8-Bromo TNP-Guanosine 5'-triphosphate tetrasodium	Fluorescent Dye	Others
8-Bromo TNP-GTP (8-Bromo TNP-Guanosine 5'-triphosphate) tetrasodium is a fluorescent TNP-GTP analogue with a TNP fluorophore and a bromo group at the 8-position. 8-Bromo TNP-GTP tetrasodium can be used to analyze the binding activity of GTP-binding proteins (such as Ras and Gα subunits) .

HY-21586A

m7GTP 7-Methyl-Guanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog	Metabolic Disease
7-Methyl-guanosine-5'-triphosphate (m7GTP) is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-175128

*8-(2-Aminoethylthio)guanosine-5'-O-triphosphate* sodium** 8-AET-GTP sodium	Drug Derivative	Metabolic Disease
8-(2-Aminoethylthio)guanosine-5'-O-triphosphate (8-AET-GTP) is a GTP (HY-113225) derivative. GTP is the energy substrate for protein synthesis and gluconeogenesis.

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium GDP-d13 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium GDP-13C10,15N5 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066B

Guanosine 5'-diphosphate ditromethamine GDP ditromethamine	Hepcidin Potassium Channel Endogenous Metabolite	Inflammation/Immunology
Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-137677

GTP-γ-S Guanosine 5'-[γ-thio]triphosphate	GLUT	Metabolic Disease
GTPγS (Guanosine 5'-[γ-thio]triphosphate) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS to couple with G- protein α, to study its effect on kinase activity. GTPγS acts as a component of lysis buffer .

HY-181453

*2'-O-Benzyl-3'-O-(N'-methylanthraniloyl)guanosine-5'-O-triphosphate* sodium** 2’-O-Benzyl-3’-MANT-GTP sodium	Drug Derivative Fluorescent Dye	Others
2'-O-Benzyl-3'-O-(N'-methylanthraniloyl) guanosine-5'-O-triphosphate sodium (Mant-GTP R=CH₃, B=Gua) (2'-O-Benzyl-3'-MANT-GTP sodium) is a methylanthraniloyl derivative of GTP (HY-113225). Methylanthraniloyl-GTP exhibits fluorescent properties (λ_max: 442 nm in water; 432 nm in ethanol) .

HY-172002

3'-O-Methylguanosine-5'-O-triphosphate sodium 3'-O-Methyl GTP sodium	Drug Derivative	Metabolic Disease
3'-O-Methylguanosine-5'-O-triphosphate (3'-O-Methyl GTP) sodium is a methylated derivative of Guanosine 5'-triphosphate (HY-W010737). 3'-O-Methylguanosine-5'-O-triphosphate has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.

HY-137674A

isoGTP sodium IsoGuanosine-5'-O-triphosphate sodium	Drug Isomer	Cancer
isoGTP (Isoguanosine-5'-O-triphosphate) sodium is an isomer of guanosine 5'-triphosphate and a phosphorylated form of Crotonoside (HY-N0071). isoGTP sodium inhibits transcription and induces T to C mutations in a reverse transcriptase assay. isoGTP sodium is promising for research of substrate specificity of phosphofructokinase and mutT homolog 1 (MTH1) .

HY-137609A

TNP-GTP tetrasodium TNP-Guanosine 5'-triphosphate tetrasodium	Glutamate Dehydrogenase (GLDH) P2X Receptor Guanylate Cyclase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
TNP-GTP tetrasodium is a fluorescently labeled GTP (HY-113225) derivative. TNP-GTP tetrasodium can inhibit glutamate dehydrogenase (K_i = 2.7 μM). TNP-GTP tetrasodium is an antagonist of the purinergic P2X₂ and P2X_2/3 receptors with IC₅₀ values of 0.4 and 1.2 nM, respectively. TNP-GTP tetrasodium also inhibit rat soluble guanylyl cyclase (K_i = 11 nM) .

HY-174162A

2'-O-Methylguanosine-5'-O-triphosphate sodium 2'-Methyl GTP sodium	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Infection
2'-O-Methylguanosine-5'-O-triphosphate sodium (2'-Methyl GTP sodium), a methylated derivative of Guanosine 5'-triphosphate (HY-W010737), is a HCV NS5B RNA-dependent RNA polymerase inhibitor. 2'-O-Methylguanosine-5'-O-triphosphate sodium is a nucleotide competitor of GTP and acts as a chain terminator to inhibit RNA synthesis. 2'-O-Methylguanosine-5'-O-triphosphate sodium can be used for HCV infections research .

Cat. No.	Product Name	Type

HY-113066C

Guanosine 5'-diphosphate sodium, 96% (HPLC) 2 Publications Verification GDP sodium, Type I, 96% (HPLC)	Biochemical Assay Reagents
Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

Guanosine 5'-diphosphate sodium, 96% (HPLC)

2 Publications Verification

GDP sodium, Type I, 96% (HPLC)

Biochemical Assay Reagents

Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-100767

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Biochemical Assay Reagents
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

HY-21586B

*7-Methyl-guanosine-5'-triphosphate* sodium** m7GTP sodium	Biochemical Assay Reagents
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA	Biochemical Assay Reagents
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-139100

*N7-Methyl-guanosine-5'-triphosphate-5'-adenosine* m7GpppA	Biochemical Assay Reagents
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010737

Guanosine-5'-triphosphate disodium salt Maximum Cited Publications 8 Publications Verification 5'-GTP disodium salt	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Exosomes Endogenous Metabolite MicroRNA
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-12695

Guanosine 5'-triphosphate trisodium 5 Publications Verification 5'-GTP trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Exosomes Endogenous Metabolite DNA/RNA Synthesis
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate trisodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Hepcidin Potassium Channel Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-113066C

Guanosine 5'-diphosphate sodium, 96% (HPLC) 2 Publications Verification GDP sodium, Type I, 96% (HPLC)	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT
Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI .

HY-12695B

Guanosine 5'-triphosphate trisodium salt hydrate Maximum Cited Publications 8 Publications Verification 5'-GTP trisodium salt hydrate	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Exosomes Endogenous Metabolite DNA/RNA Synthesis
Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-113066

Guanosine 5'-diphosphate GDP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder Source Classification	Hepcidin Potassium Channel Endogenous Metabolite Interleukin Related STAT
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-113066AR

Guanosine 5'-diphosphate disodium salt (Standard) GDP disodium salt (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Hepcidin Endogenous Metabolite Potassium Channel Reference Standards
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

Cat. No.	Product Name	Chemical Structure

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-150768S

Guanosine 5'-triphosphate (GTP), ammonium salt-d27
Guanosine 5'-triphosphate (GTP), ammonium salt-d₂₇ is the deuterium labeled Guanosine 5'-triphosphate (GTP), ammonium salt .

HY-150773S

Guanosine 5'-triphosphate(GTP)-d4 ammonium salt
Guanosine 5'-triphosphate(GTP)-d₄ (ammonium salt) is the deuterium labeled Guanosine 5'-triphosphate(GTP) ammonium salt .

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium

Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-150796S

Guanosine 5'-triphosphate, ammonium salt-15N5
Guanosine 5'-triphosphate, ammonium salt- ¹⁵N₅ is the ¹⁵N labeled Guanosine 5'-triphosphate, ammonium salt .

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium

Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

Cat. No.	Product Name		Classification

HY-W010737

Guanosine-5'-triphosphate disodium salt Maximum Cited Publications 8 Publications Verification 5'-GTP disodium salt		Nucleotide Analogs
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-12695

Guanosine 5'-triphosphate trisodium 5 Publications Verification 5'-GTP trisodium		Nucleotide Analogs
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate trisodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt		Nucleotide Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-12695B

Guanosine 5'-triphosphate trisodium salt hydrate Maximum Cited Publications 8 Publications Verification 5'-GTP trisodium salt hydrate		Nucleotide Analogs
Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration .

HY-113066

Guanosine 5'-diphosphate GDP		Nucleotide Analogs
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO₄. Guanosine 5'-diphosphate can be used in the research of AI .

HY-21586B

*7-Methyl-guanosine-5'-triphosphate* sodium** m7GTP sodium		Nucleotide Analogs Guanine Nucleotide
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-139100B

m7G(5')ppp(5')A diammonium m7GpppA diammonium; N7-Methyl-Guanosine-5'-triphosphate-5'-adenosine diammonium		Cap Analogs Cap Analogs
m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-139101A

Guanosine 5'-triphosphate-5'-adenosine triammonium GpppA triammonium		Nucleotide Analogs Adenine Nucleotide
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA		Nucleotide Analogs Adenine Nucleotide
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-139100

*N7-Methyl-guanosine-5'-triphosphate-5'-adenosine* m7GpppA		Cap Analogs
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-21586

*7-Methyl-guanosine-5'-triphosphate* disodium** m7GTP disodium		Nucleotide Analogs Guanine Nucleotide
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-154121

*2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate* ammonium**		Nucleoside Analogs Guanosine
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-21586A

m7GTP 7-Methyl-Guanosine-5'-triphosphate		Nucleoside Analogs Nucleotide Analogs
7-Methyl-guanosine-5'-triphosphate (m7GTP) is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-172002

3'-O-Methylguanosine-5'-O-triphosphate sodium 3'-O-Methyl GTP sodium		Nucleotide Analogs Guanine Nucleotide
3'-O-Methylguanosine-5'-O-triphosphate (3'-O-Methyl GTP) sodium is a methylated derivative of Guanosine 5'-triphosphate (HY-W010737). 3'-O-Methylguanosine-5'-O-triphosphate has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.

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