30 Results for "

HEK293 cell line

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "HEK293 cell line" in MCE Product Catalog:

33
33 Publications Verification
Cat. No.: HY-12033
CAS No.: 362-07-2
Purity:  99.76%
Synonyms: 2-ME2; NSC-659853
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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16
16 Cited Publications
Cat. No.: HY-15888
CAS No.: 315704-66-6
Purity:  99.76%
Target:  

BMI1 Autophagy

Research Areas:  

Cancer

PTC-209 is a specific BMI-1 inhibitor with an IC50 of 0.5 μM in HEK293T cell line. PTC-209 irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 shows potent anti-myeloma activity and impairs the tumor microenvironment .
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16
16 Cited Publications
Cat. No.: HY-15888A
CAS No.: 1217022-63-3
Purity:  99.44%
Target:  

BMI1 Autophagy

Research Areas:  

Cancer

PTC-209 hydrobromide is a specific BMI-1 inhibitor with an IC50 of 0.5 μM in HEK293T cell line. PTC-209 hydrobromide irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 hydrobromide shows potent anti-myeloma activity and impairs the tumor microenvironment .
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1
1 Cited Publications
Cat. No.: HY-P73074
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDNF; ATF2; Glial cell Derived Neurotrophic Factor; ATF; Astrocyte-Derived Trophic Factor; Glial cell line Derived Neurotrophic Factor; Glial cell line-Derived Neurotrophic Factor; Glial Derived Neurotrophic Factor; HFB1-GDNF; HSCR3; ATF1; HGDNF
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-145267
CAS No.: 2406278-81-5
Purity:  99.59%
Target:  

PARP Wnt

Research Areas:  

Cancer

OM-153 is a potent and orally active tankyrase inhibitor with IC50s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 (TNKS1/2), respectively. OM-153 inhibits luciferase-based Wnt/β-catenin signaling reporter activity with an IC50 value of 0.63 nM. OM-153 shows inhibition of Wnt/β-catenin signaling and proliferation in COLO 320DM .
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Cat. No.: HY-12033S2
CAS No.: 358731-34-7
Purity:  98.67%
Synonyms: 2-ME2-d5; NSC-659853-d5
2-Methoxyestradiol-d5 is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-179475
CAS No.: 1262781-19-0
Target:  

CaSR

Research Areas:  

Endocrinology

KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC50 of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .
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Cat. No.: HY-12033S1
Synonyms: 2-ME2-13C6; NSC-659853-13C6
2-Methoxyestradiol- 13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-12033S
CAS No.: 1217470-09-1
2-Methoxyestradiol- 13C,d3 is the 13C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-157935
CAS No.: 2225109-18-0
Target:  

17β-HSD

Research Areas:  

Neurological Disease

17β-HSD10-IN-3 (compound 23) is a 17β-HSD10 inhibitor with the IC50 of 5.59 μM. 17β-HSD10-IN-3 shows no cell cytotoxicity toward the HEK-293 cell line up to 20 μM .
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Cat. No.: HY-145266
CAS No.: 2406276-78-4
Target:  

PARP

Research Areas:  

Cancer

OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM) .
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Cat. No.: HY-12033R
CAS No.: 362-07-2
Synonyms: 2-ME2 (Standard); NSC-659853 (Standard)
2-Methoxyestradiol (Standard) is the analytical standard of 2-Methoxyestradiol. This product is intended for research and analytical applications. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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Cat. No.: HY-168074
4″-C18 EGCG is a potent inhibitor of α-amylase and α-glucosidase with IC50 values of 3.74 and 0.81 μM, respectively. 4″-C18 EGCG inhibits carbohydrate hydrolases, reduces oxidative stress and inflammation, and exhibits antidiabetic activity. 4″-C18 EGCG also downregulates proinflammatory cytokines and is cytotoxic to primary human peripheral blood mononuclear cells (PBMCs), non-cancer cell lines 3T3-L1, and HEK 293 at 50 μM .
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Cat. No.: HY-P75169
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDNF; ATF2; Glial cell Derived Neurotrophic Factor; ATF; Astrocyte-Derived Trophic Factor; Glial cell line Derived Neurotrophic Factor; Glial cell line-Derived Neurotrophic Factor; Glial Derived Neurotrophic Factor; HFB1-GDNF; HSCR3; ATF1; HGDNF
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P704369
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GDNF; ATF2; Glial cell Derived Neurotrophic Factor; ATF; Astrocyte-Derived Trophic Factor; Glial cell line Derived Neurotrophic Factor; Glial cell line-Derived Neurotrophic Factor; Glial Derived Neurotrophic Factor; HFB1-GDNF; HSCR3; ATF1; HGDNF
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76360
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial cell line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76948
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial cell line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P76949
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial cell line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P77371
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial cell line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF R
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P70192
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA2; RET Ligand 2; GDNF Family Receptor Alpha 2; GDNFR-Beta; GDNFRB; NTNR-Alpha; RETL2; Glial cell line Derived Neurotrophic Factor Receptor, Beta; TRNR2; PI-Linked cell-Surface Accessory Protein; GDNF Family Receptor Alpha-2; TRN Receptor, GPI-Anchored
Species:  
Human
Source:  
HEK293
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