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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
HTLA cell
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "HTLA cell" in MCE Product Catalog:
Cat. No.: HY-163671
CAS No.: 2767348-36-5
Research Areas:
PW0729 is a selective GPR52 agonist. PW0729 activates G protein/cAMP signaling pathway, with bias toward this pathway over β-arrestin recruitment, and induces GPR52 desensitization. PW0729 can be used for the research of neuropsychiatric and neurological diseases .
Cat. No.: HY-181540
Target:
Research Areas:
YL-GB063 is an Apelin receptor (APJ) antagonist. YL-GB063 inhibits Apelin-induced APJ β-arrestin recruitment (IC50 of 3.1 μM in HTLA cells). YL-GB063 has anti-cancer activity against ovarian cancer .
Cat. No.: HY-184476
CAS No.: 2084834-44-4
Target:
Research Areas:
SLL-022CCP is a KOR-selective, high affinity and extremely potent agonist with an EC50 of 9.1 nM and a Ki of 2.0 nM. SLL-022CCP inhibits cAMP production with an EC50 of 0.002 nM, and exhibits high receptor subtype selectivity over the μ-opioid receptor (MOR, EC50 = 1.6 nM) and δ-opioid receptor (DOR, EC50 = 30.0 nM). SLL-022CCP exhibits robust antinociceptive and antipruritic effects with low central side effects .
Cat. No.: HY-181515
Target:
Research Areas:
KOR agonist 8 (Compound 8a) is a κ-opioid receptor (KOR) agonist and an analgesic agent, with a Ki value of 5.3 nM for human KOR, and EC50 values of 43.1 nM and 9236 nM for human KOR. It exhibits subtype selectivity for MOR/KOR and DOR/KOR. KOR agonist 8 is applicable for pain-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
