1 Result for "

ICRF192

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ICRF192" in MCE Product Catalog:

Cat. No.: HY-183524
CAS No.: 58893-33-7
Target:  

Topoisomerase

Research Areas:  

Cardiovascular Disease

ICRF 192 is a weak DNA topoisomerase II (DNA topoisomerase II) inhibitor with an IC50 of 91 μM. ICRF 192 forms an iron-chelating derivative via ring-opening hydrolysis, which can displace Fe 3+ from the Fe 3+-doxorubicin complex. ICRF 192 is used for studies on the structure-activity relationship of bisdioxopiperazines and the cardiotoxicity of anthracycline drugs .
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