1 Result for "

IITZ02

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IITZ02" in MCE Product Catalog:

Cat. No.: HY-203817
CAS No.: 1807988-46-0
Domaines de recherche:  

Cancer

IITZ-02 is a lysosomotropic Autophagy inhibitor. IITZ-02 enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally inducing the inhibition of autophagy. IITZ-02 abolishes mitochondrial membrane potential and induces apoptosis through the mitochondria-mediated pathway. IITZ-02 has a potent antitumor activity in MDA-MB-231 xenograft mouse models. IITZ-02 can be used for cancers research .
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