3 Results for "

IL-33/ST2 pathway

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "IL-33/ST2 pathway" in MCE Product Catalog:

Cat. No.: HY-168532
CAS No.: 3099811-61-4
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
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Cat. No.: HY-P99729
CAS No.: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Melrilimab (GSK 3772847; CNTO-7160) is a humanized IgG2σ monoclonal antibody that targets the IL-33 receptor ST2 and blocks the IL-33/ST2 signaling pathway by binding to the ST2 protein. Melrilimab is applicable to research related to asthma and atopic dermatitis .
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Cat. No.: HY-P991633

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research .
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