2 Results for "

Inavolisib

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Inavolisib" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-101562
CAS No.: 2060571-02-8
Purity:  99.96%
Synonyms: GDC-0077; RG6114
Target:  

PI3K Apoptosis

Research Areas:  

Cancer

Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor (IC50=0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib can be used for the study of breast cancer .
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Cat. No.: HY-101562R
CAS No.: 2060571-02-8
Synonyms: GDC-0077 (Standard); RG6114 (Standard)
Research Areas:  

Cancer

Inavolisib (Standard) is the analytical standard of Inavolisib (HY-101562). This product is intended for research and analytical applications. Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor (IC50=0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib can be used for the study of breast cancer .
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