2 Results for "

KD014

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KD014" in MCE Product Catalog:

Cat. No.: HY-P991316
Synonyms: DX-2400; DX-2410

Target:  

MMP NO Synthase

Research Areas:  

Inflammation/Immunology Cancer

KD014 (DX-2400) is a human monoclonal antibody that selectively targets MMP‑14. KD014 inhibits collagen degradation and regulates the polarization of macrophages toward an anti-inflammatory/anti-tumor phenotype. KD014 alleviates joint damage in rheumatoid arthritis and suppresses tumor growth and invasion. KD014 can be used in studies related to breast cancer and rheumatoid arthritis .
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Cat. No.: HY-P10570
CAS No.: 2042178-19-6
Research Areas:  

Cancer

[Nle20] H4 peptide (16−23) is a peptide with strong inhibitory activity against histone methyltransferase SETD8 (Kd=0.14 μM), which inhibits SETD8's methylation of histone H4 by competing with SETD8's substrate binding site. [Nle20] H4 peptide (16−23) can be used as a lead compound for anticancer therapy .
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