[Nle20] H4 peptide (16−23)
[Nle20] H4 peptide (16−23) is a peptide with strong inhibitory activity against histone methyltransferase SETD8 (Kd=0.14 μM), which inhibits SETD8's methylation of histone H4 by competing with SETD8's substrate binding site. [Nle20] H4 peptide (16−23) can be used as a lead compound for anticancer therapy.
For research use only. We do not sell to patients.
- CAS No.: 2042178-19-6
- Formula: C47H88N20O9
- Molecular Weight:1077.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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CAS No. 2042178-19-6
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Molecular Weight 1077.33
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Formula C47H88N20O9
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Sequence
Lys-Arg-His-Arg-{Nle}-Val-Leu-Arg
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Sequence Shortening
KRHR-{Nle}-VLR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)