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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
KRAS G12C degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "KRAS G12C degrader-1" in MCE Product Catalog:
Cat. No.: HY-153881
CAS No.: 2768099-51-8
KRAS G12C degrader-1 is a potent KRAS G12C degrader (DC50 < 100 nM). KRAS G12C degrader-1 is an HSP90-mediated CHAMP (chaperone-assisted protein degrader) that induces KRAS G12C degradation via a chaperone-mediated mechanism. KRAS G12C degrader-1 can be used in research related to non-small cell lung cancer .
Cat. No.: HY-176489
CAS No.: 3043908-63-7
PROTAC pan-KRAS degrader-1 is a pan-KRAS-targeting PROTAC degrader for degrading different KRAS mutation types, such as G12D, G12C, G12V, and G13D. PROTAC pan-KRAS degrader-1 potently degrades KRAS mutation (G12D) in AGS cells, with a DC50 of 1.1 nM, Dmax of 95%. PROTAC pan-KRAS degrader-1 can be used to search diseases caused by KRAS mutation or amplification, especially cancers such as breast cancer, bladder cancer, gastric cancer, etc .
Research Areas:
Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRAS G12C degrader .
Cat. No.: HY-153880
CAS No.: 2795275-59-9
KRAS degrader-1 is a potent KRAS degrader. KRAS degrader-1 targets specific proteins for degradation via the autophagy-lysosomal degradation pathway. KRAS degrader-1 is suitable for use in cancer research. (Blue: KRAS G12C-IN-72 (HY-128414); Black: Linker (HY-175587); Pink: 5-Iodoindolin-2-one (HY-76986); Blue + Black: KRAS ligand-Linker Conjugate 7 (HY-175586)) .
Cat. No.: HY-170326
CAS No.: 1207597-54-3
Research Areas:
Hsp90-in-35 is an inhibitor of Hsp90, with an IC50 between 0.05 and 0.5 μM. HSP90-IN-35 has antitumor activity. HSP90-IN-35 can be used to synthesize KRAS G12C degrader-1 (PROTAC) (HY-153881) .
Cat. No.: HY-151014
CAS No.: 1698025-19-2
Research Areas:
KRAS ligand 1 is a KRAS G12C ligand and can be used for the synthesis of PROTACs, such as PROTAC KRAS G12C degrader-1 (HY-139186) .
Cat. No.: HY-128414
CAS No.: 2326523-41-3
Research Areas:
KRAS G12C-IN-72 (Example 571) is a KRAS G12C inhibitor. KRAS G12C-IN-72 can be used as a target protein ligand to synthesize PROTACs, such as KRAS degrader-1 (HY-153880). KRAS G12C-IN-72 can be used in cancer research .
Cat. No.: HY-178076
CAS No.: 2414414-60-9
Research Areas:
Pomalidomide-C12-NH2 is a conjugate of an E3 ligase and a linker, which can be used for the synthesis of PROTACs, such as PROTAC KRAS G12C degrader-1 (HY-139186) .
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Protocols
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