KRAS degrader-1
KRAS degrader-1 is a potent KRAS degrader. KRAS degrader-1 targets specific proteins for degradation via the autophagy-lysosomal degradation pathway. KRAS degrader-1 is suitable for use in cancer research. (Blue: KRAS G12C-IN-72 (HY-128414); Black: Linker (HY-175587); Pink: 5-Iodoindolin-2-one (HY-76986); Blue + Black: KRAS ligand-Linker Conjugate 7 (HY-175586)).
For research use only. We do not sell to patients.
- CAS No.: 2795275-59-9
- Formula: C55H57Br2ClFIN8O7
- Molecular Weight:1283.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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K-RAS |
KRAS degrader-1 (Compound 1) is a potent KRAS degrader that targets specific proteins for degradation through the autophagy-lysosomal degradation pathway[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2795275-59-9
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Molecular Weight 1283.25
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Formula C55H57Br2ClFIN8O7
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SMILES
BrC(C=C(C=C1Br)/C=C2C3=CC(I)=CC=C3NC/2=O)=C1OCCOCCOCCOCCCN(CCC4)[C@@H]4COC5=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C7C(CN(C8=CC=CC9=C8C(Cl)=CC=C9)CC7)=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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