1 Result for "

KRAS G13D-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRAS G13D-IN-1" in MCE Product Catalog:

Cat. No.: HY-161066
Target:  

Ras

Research Areas:  

Cancer

KRAS G13D-IN-1 (Compound 41) is a selective and covalently reversible inhibitor of KRAS G13D (IC50: 0.41 nM). The selectivity for KRAS G13D is 29-fold against KRAS wild type. KRAS G13D-IN-1 is an inhibitor of the GDP state and targets the SWII binding pocket of KRAS G13D. KRAS G13D-IN-1 inhibits KRAS binding to GDP and turns on/off downstream signaling cascades. KRAS G13D-IN-1 can be used in the research of colon cancer .
loading...
    loading...