1 Result for "

KRAS-IN-65

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRAS-IN-65" in MCE Product Catalog:

Cat. No.: HY-189666
CAS No.: 3101978-77-9
Target:  

Ras

Research Areas:  

Cancer

KRAS-IN-65 is an orally active KRAS inhibitor. KRAS-IN-65 inhibits KRAS G12D/G12V signaling with IC50 values of 20 nM and 5 nM, respectively. KRAS-IN-65 exhibits reduced glucuronidation and intestinal stability. KRAS-IN-65 produces limited tumor growth inhibition in xenograft models. KRAS-IN-65 can be used for cancer-related research, such as non-small cell lung cancer and colorectal cancer .
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