1 Result for "

LBA3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LBA3" in MCE Product Catalog:

Cat. No.: HY-158160
CAS No.: 2918263-09-7
Target:  

Sodium Channel

Research Areas:  

Metabolic Disease

LBA-3 is a selective, orally active inhibitor for sodium-coupled citrate transporter SLC13A5, with an IC50 of 67 nM. LBA-3 decreases levels of triglyceride and total cholesterol in oleic and palmitic acid (OPA)-stimulated AML12 cells, PCN-stimulated primary mouse hepatocytes and in mouse models, without detectable toxicity. LBA-3 is blood-brain barrier permeable .
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