1 Result for "

LUT014

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LUT014" in MCE Product Catalog:

Cat. No.: HY-111940
CAS No.: 2274819-46-2
Purity:  97.23%
Target:  

Raf p38 MAPK ERK

Research Areas:  

Inflammation/Immunology

LUT014 is a topical inhibitor targeting BRAF that cannot pass through the blood-brain barrier. LUT014 inhibits BRAF kinase and abnormally activates the MAPK/ERK signaling pathway, promoting the proliferation of epidermal keratinocytes, repairing skin barrier damage caused by radiation damage, and alleviating inflammatory responses. LUT014 is independent of RAS signaling and accelerates the repair and regeneration of damaged skin cells. LUT014 can be used to study radiation dermatitis, especially skin damage caused by breast cancer radiotherapy .
loading...
    loading...