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Labiatae

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By Targets:	Aldose Reductase (1) Apoptosis (2) EGFR (2) Endogenous Metabolite (1) Insecticide (1) NO Synthase (1) Reference Standards (1)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0211

Cyasterone 2 Publications Verification	EGFR Apoptosis	Cancer
Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors .

HY-151231

6-Hydroxyluteolin	Aldose Reductase	Neurological Disease Metabolic Disease
6-Hydroxyluteolin (Compound 17) is a flavonoid derivative and also an inhibitor of Aldose reductase, with an experimental -log IC₅₀ value of 6.690. 6-Hydroxyluteolin can be isolated from the leaves of multiple plant families, including Plantaginaceae, Globulariaceae and Labiatae. 6-Hydroxyluteolin serves as a phylogenetic marker for higher plants. 6-Hydroxyluteolin can be used in the research of diabetic cataract .

HY-N1257

Sculponeatin B	Others	Others
Sculponeatin B is a diterpenoid compound from the plant of the genus Rabdosia, Labiatae .

HY-N2969

Bulleyanin	Others	Others
Bulleyanin is a compound isolated from isodon species (Labiatae) .

HY-N1263

Scutebarbatine X	NO Synthase	Inflammation/Immunology
Scutebarbatine X (Compound 2) is a neo-clerodane diterpenoids isolated from Scutellaria barbatae (Labiatae) and has anti-inflammatory properties .

HY-N0211R

Cyasterone (Standard)	Reference Standards EGFR Apoptosis	Cancer
Cyasterone (Standard) is the analytical standard of Cyasterone. This product is intended for research and analytical applications. Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors .

HY-N1671

2',5,6',7-Tetraacetoxyflavanone	Others	Infection
2',5,6',7-Tetraacetoxyflavanone is an extract isolated from Scutellaria baicalensis. 2',5,6',7-Tetraacetoxyflavanone shows significant antibacterial activity against gram-positive bacteria. 2',5,6',7-Tetraacetoxyflavanone can be used to study the treatment of inflammatory diseases .

HY-N1672

5,7,2′,6′-Tetrahydroxyflavanone	Others	Infection
5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases .

HY-118989

Ajugalactone	Insecticide Endogenous Metabolite	Infection
Ajugalactone is a phytoecdysteroid found in plants of the Ajuga genus. Ajugalactone shows both ecdysone (HY-N0179) agonist activity and anti‑ponasterone A (HY-N1534) antagonist activity. Ajugalactone significantly disrupts insect molting and developmental processes. Ajugalactone acts as an insect growth regulator that interferes with insect molting. Ajugalactone induces complete mortality in first‑instar larvae of the greenhouse whitefly. Ajugalactone can be used for research on insect‑plant interactions and insect growth regulation .

Cyasterone 2 Publications Verification	Classification of Application Fields Crotalaria sessiliflora L. Labiatae Amaranthaceae Plants Disease Research Fields Achyranthes bidentata Steroids Cancer Source Classification	EGFR Apoptosis
Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors .

Sculponeatin B	Classification of Application Fields Eysenhardtia texana Scheele Labiatae Other Diseases Plants Disease Research Fields Source Classification	Others
Sculponeatin B is a diterpenoid compound from the plant of the genus Rabdosia, Labiatae .

Bulleyanin	Natural Products Classification of Application Fields Labiatae Other Diseases Plants Disease Research Fields Dalbergia frutescens (Vell.) Britton Source Classification	Others
Bulleyanin is a compound isolated from isodon species (Labiatae) .

Scutebarbatine X	Terpenoids Labiatae Derris robusta Diterpenoids Plants Source Classification	NO Synthase
Scutebarbatine X (Compound 2) is a neo-clerodane diterpenoids isolated from Scutellaria barbatae (Labiatae) and has anti-inflammatory properties .

Cyasterone (Standard)	Structural Classification Crotalaria sessiliflora L. Labiatae Amaranthaceae Plants Achyranthes bidentata Steroids Source Classification	Reference Standards EGFR Apoptosis
Cyasterone (Standard) is the analytical standard of Cyasterone. This product is intended for research and analytical applications. Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors .

2',5,6',7-Tetraacetoxyflavanone	Structural Classification Flavonoids Labiatae Flavonones Plants Medicago truncatula Gaertn. Source Classification	Others
2',5,6',7-Tetraacetoxyflavanone is an extract isolated from Scutellaria baicalensis. 2',5,6',7-Tetraacetoxyflavanone shows significant antibacterial activity against gram-positive bacteria. 2',5,6',7-Tetraacetoxyflavanone can be used to study the treatment of inflammatory diseases .

5,7,2′,6′-Tetrahydroxyflavanone	Structural Classification Flavonoids Labiatae Flavonones Plants Medicago truncatula Gaertn. Source Classification	Others
5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases .

Ajugalactone	Structural Classification Labiatae Plants Steroids Carphephorus corymbosus (Nutt.) Torr. & A.Gray Source Classification	Insecticide Endogenous Metabolite
Ajugalactone is a phytoecdysteroid found in plants of the Ajuga genus. Ajugalactone shows both ecdysone (HY-N0179) agonist activity and anti‑ponasterone A (HY-N1534) antagonist activity. Ajugalactone significantly disrupts insect molting and developmental processes. Ajugalactone acts as an insect growth regulator that interferes with insect molting. Ajugalactone induces complete mortality in first‑instar larvae of the greenhouse whitefly. Ajugalactone can be used for research on insect‑plant interactions and insect growth regulation .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Labiatae

Inhibitors & Agonists

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Natural
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