2. Search Result
Search Result
Results for "

Legionella pneumophila

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Fluorescent Dyes

5

Peptides

2

Natural
Products

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13451
    Finafloxacin
    1 Publications Verification

    		 Antibiotic Bacterial Infection
    Finafloxacin is an orally active fourth-generation fluoroquinolone broad-spectrum antibiotic. Finafloxacin exhibits stronger antibacterial activity in acidic pH environments and is not easily affected by bacterial multidrug efflux transporters. Finafloxacin is effective against a variety of extracellular pathogenic bacteria, and can also accumulate in macrophages, showing excellent antibacterial activity against intracellular Staphylococcus aureus, Listeria monocytogenes, Legionella pneumophila, Burkholderia pseudomallei, and other pathogens. Finafloxacin has been approved by the U.S. FDA for research on acute otitis externa mediated by Pseudomonas aeruginosa. Finafloxacin is also used in studies related to diseases such as melioidosis, inhalational tularemia, and inhalational plague .
    Finafloxacin
  • HY-D1191
    SYBR green I chloride
    3 Publications Verification

    		 Fluorescent Dye DNA/RNA Synthesis Others
    SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .
    SYBR green I chloride
  • HY-135477
    RWJ-60475

    		Phosphatase Bacterial Infection
    RWJ-60475 is a cell-permeable tyrosine phosphatase inhibitor with an IC50 of 3.3 μM. RWJ-60475, by inhibiting the activity of CD45/CD148 phosphatase, interferes with the phagocytic function of macrophages, thereby blocking the invasion of Legionella pneumophila into host cells and the transport of effector proteins. RWJ-60475 significantly reduces the uptake of bacterial particles by macrophages. RWJ-60475 can be used in the research of anti-infection targeting host factors .
    RWJ-60475
  • HY-P5599
    Temporin K

    		Bacterial Infection
    Temporin K is an antimicrobial peptide against Legionella pneumophila .
    Temporin K
  • HY-P5598
    Temporin G

    		Bacterial Infection
    Temporin G is an antimicrobial peptide against Legionella pneumophila .
    Temporin G
  • HY-P5595
    Temporin C

    		Bacterial Infection
    Temporin C is an antimicrobial peptide against Legionella pneumophila .
    Temporin C
  • HY-P5597
    Temporin F

    		Bacterial Infection
    Temporin F is an antimicrobial peptide against Legionella pneumophila .
    Temporin F
  • HY-114505
    3-Hydroxypentadecane-4-one

    		Bacterial Infection
    3-Hydroxypentadecane-4-one (LAI-1; Legionella autoinducer-1) is a quorum sensing signaling molecule by Legionella pneumophila. 3-Hydroxypentadecane-4-one is an autoinducer, which affects the intercellular communication between bacteria through sensor kinases, LqsS, LqsT and LqsR .
    3-Hydroxypentadecane-4-one
  • HY-105213
    YM-17K

    MC-352

    		 Antibiotic Bacterial Infection
    YM-17K (MC-352) is a macrolide antibiotic. YM-17K exhibits antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and anaerobic bacteria. YM-17K exhibits stable activity in serum and is less affected by pH values .
    YM-17K
  • HY-B1894R
    Cefetamet pivoxyl (Standard)

    Ro 15-8075 free base (Standard)

    		 Bacterial Reference Standards Antibiotic Infection
    Cefetamet pivoxyl (Standard) is the analytical standard of Cefetamet pivoxyl. This product is intended for research and analytical applications. Cefetamet pivoxyl is a cephalosporin antibiotic. Cefetamet pivoxyl inhibits 355 enteropathogens Keime, Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila .
    Cefetamet pivoxyl (Standard)
  • HY-174313
    Antibacterial agent 284

    		Bacterial Toll-like Receptor (TLR) Collagen Infection Inflammation/Immunology
    Antibacterial agent 284 (Compound 7) is an Antibacterial agent. Antibacterial agent 284 has a zinc-binding structure and potent inhibitory activity against Legionella pneumophila metalloprotease ProA (IC50: 0.96 μM) with zinc-binding structure. Antibacterial agent 284 significantly inactivates the cleavage of collagen IV and flagellin (ProA substrates) and reduces immune evasion from the TLR5-NF-κB pathway and PMN-mediated inflammation in human lung tissue explants. Antibacterial agent 284 is promising for Legionnaires' disease research .
    Antibacterial agent 284
  • HY-B1894
    Cefetamet pivoxyl

    Ro 15-8075 free base

    		 Antibiotic Bacterial Infection
    Cefetamet pivoxyl (Ro 15-8075 free base) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, *Neisseria*, *Haemophilus*) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
    Cefetamet pivoxyl
  • HY-W093433
    2,2-Dibromo-2-cyanoacetamide

    		Environmental Pollutants Bacterial Infection
    2,2-Dibromo-2-cyanoacetamide is a non-oxidizing bactericide. 2,2-Dibromo-2-cyanoacetamide enhances bactericidal activity by reacting with sulfhydryl groups on the cell walls of microorganisms in aquatic environments to release bromide ions. 2,2-Dibromo-2-cyanoacetamide effectively inactivates Legionella pneumophila, rendering it non-culturable, and exhibits significantly higher killing efficacy against this bacterium in reservoir biofilms than in aerosol biofilms. 2,2-Dibromo-2-cyanoacetamide is suitable for legionellosis prevention and control as well as related research .
    2,2-Dibromo-2-cyanoacetamide
  • HY-N15140
    α-Thujaplicin

    		Drug Isomer Bacterial Fungal Carboxypeptidase Infection Cancer
    α-Thujaplicin, the isomer of Hinokitiol (HY-B2230), is an antimicrobial agent. α-Thujaplicin can be isolated from Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO). α-Thujaplicin shows inhibition of Carboxypeptidase A (IC50: 32.4 μM). α-Thujaplicin shows rather strong antifungal activity against seven kinds of plant-pathogenic fungi, their MICs being in the range of 12.0-50.0 μg/mL. α-Thujaplicin shows clear antibacterial activity against Legionella pneumophila SG 1 and L. pneumophila SG 3, and their MICs are in the range of 12.5-50 μg/mL. α-Thujaplicin shows antibacterial activity against Enterococcus faecalis IFO-12965 with a MIC of 1.56 μg/mL. α-Thujaplicin shows germination inhibition toward the seed of Echinochloa utilis Ohwi et Yabuno. α-thujaplicin inhibits lymphocytic leukemia, stomach cancer, Ehrlich’s ascites carcinoma .
    α-Thujaplicin

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: