1 Result for "

Libvatrep

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Libvatrep" in MCE Product Catalog:

Cat. No.: HY-114017
CAS No.: 871814-52-7
Purity:  99.54%
Synonyms: SAF312; Vanilloid receptor antagonist 1
Target:  

TRP Channel

Research Areas:  

Neurological Disease

Libvatrep (SAF312) is a non-competitive TRPV1 antagonist with an IC50 of 0.35-0.69 µM in HEK293T cells. It binds to the vanilloid pocket and an allosteric site, preventing S4/S5 conformational changes and channel opening. Libvatrep can be used for research on ocular surface pain and eye pain after photorefractive keratectomy .
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