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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
M 04
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "M 04" in MCE Product Catalog:
10
10 Cited Publications
Cat. No.: HY-P80438
Synonyms: A26C1A antibody;
A26C1B antibody;
ACTB antibody;
ACTB_HUMAN antibody;
Actin beta antibody;
Actin cytoplasmic 1 antibody;
Actin, cytoplasmic 1, N-terminally processed antibody;
Actx antibody;
b actin antibody;
Beta cytoskeletal actin antibody;
Beta-actin antibody;
BRWS1 antibody;
E430023M04Rik antibody;
MGC128179 antibody;
PS1TP5 binding protein 1 antibody;
PS1TP5BP1 antibody;
β-actin antibody
Cat. No.: HY-168384
CAS No.: 875158-73-9
Target:
Research Areas:
M04 is an agonist of STING. It induces the expression of the IFN reporter gene in HEK293T cells expressing wild-type human STING, but does not induce this expression in HEK293T cells expressing the R71H-G230A-R293Q (HAQ) STING variant or in mouse RAW 264.7 cells, indicating that its activity is dependent on allelic and species variations. M04 induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human peripheral blood mononuclear cells (PBMCs). At a concentration of 50 µM, M04 stimulates dendritic cells isolated from PBMCs to express the MHC class II cell surface receptor HLA-DR and co-stimulatory molecules CD40, CD80, and CD86, and also enhances their ability to activate T cells in an ex vivo assay. M04 can be used in research on inflammatory immune diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
