2 Results for "

M4344

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "M4344" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-136270
CAS No.: 1613191-99-3
Purity:  99.77%
Synonyms: VX-803; M4344; ATR inhibitor 2
Target:  

ATM/ATR

Research Areas:  

Cancer

Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity .
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Cat. No.: HY-136270S
CAS No.: 1792214-00-6
Synonyms: VX-803-d8; M4344-d8; ATR inhibitor 2-d8
Gartisertib-d8 (VX-803-d8) is the deuterium labeled Gartisertib (HY-136270). Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity .
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