2 Results for "

MEN10207

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MEN10207" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-151413
CAS No.: 126050-12-2
Purity:  99.69%
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

MEN 10207 is a selective NK-2 tachykinin receptor (Neurokinin Receptor) antagonist. MEN 10207 has pA2 values of 5.2, 7.9 and 4.9 in three monoreceptor in vitro assays for NK-1, NK-2 and NK-3 tachykinin receptors, respectively.
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Cat. No.: HY-151413A
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

MEN 10207 (acetate) is a selective antagonist of the NK-2 tachykinin receptor. MEN 10207 (acetate) induces tachykinin-induced contractions in rat bladder and guinea pig airways in vivo. MEN 10207 (acetate) inhibits [β-Ala 8 ]-NKA (4-10)-induced enhancement of bladder motility in anesthetized rats and [β-Ala 8 ]-NKA (4-10)-induced enhancement of bronchoconstriction in anesthetized guinea pigs .
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