1 Result for "

MJ04

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MJ04" in MCE Product Catalog:

Cat. No.: HY-161618
CAS No.: 2099014-23-8
Target:  

JAK EGFR PI3K IGF-1R GSK-3

MJ04 is a selective inhibitor for Janus Kinase 3 (JAK 3) with an IC50 of 2.03 nM. MJ04 inhibits T cell differentation and inhibits the proinfammatory cytokines in Lipopolysaccharides (HY-D1056)‑induced macrophages. MJ04 exhibits good pharmacokinetic characters in mice, promotes hair growth in DHT-induced androgenetic alopecia (AGA) in athymic mice model, without significant toxicity (LD50 >2 g/kg) .
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