1 Result for "

MK905

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MK905" in MCE Product Catalog:

Cat. No.: HY-155995
CAS No.: 2762209-68-5
Synonyms: MK-905
Domaines de recherche:  

Cancer

Pro-905 is a phosphite peptide with antitumor activity. Pro-905 delivers the active nucleotide antimetabolite thioguanosine monophosphate (TGMP) to the tumor. Pro-905 effectively prevents incorporation of purine salvage substrates into nucleic acids and inhibits colony formation in human malignant peripheral nerve sheath tumors (MPNST) cells. Pro-905 inhibits purine salvage incorporation to nucleic acids and prevents cell growth. Pro-905 inhibits the growth of MPNST and enhances the anti-tumor efficacy of JHU395 (HY-124778) .
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