1 Result for "

ML115

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML115" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-111152
CAS No.: 912798-42-6
Purity:  99.89%
Target:  

STAT

Research Areas:  

Cancer

ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .
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