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Cat. No.: HY-111152R

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ML115 (Standard)

ML115 (Standard) is the analytical standard of ML115 (HY-111152). This product is intended for research and analytical applications. ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC₅₀ of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers.

For research use only. We do not sell to patients.

CAS No.: 912798-42-6
Formula: C₁₅H₁₅ClN₂O₄
Molecular Weight:322.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ML115 (Standard) Chemical Structure

CAS No.: 912798-42-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 912798-42-6
Molecular Weight 322.74
Formula C₁₅H₁₅ClN₂O₄
SMILES

O=C(C1=NOC(C2CC2)=C1)NC3=CC(OC)=C(Cl)C=C3OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jinzhong Wang MS, et al. STAT3/FoxO3a/Sirt1 pathway inhibition by ginsenoside Rc ameliorates cardiomyocyte damage in septic cardiomyopathy by altering macrophage polarization. J Mol Histol. 2025 Apr 28;56(3):148. [Content Brief]

[2]. Madoux F, et al. Modulators of STAT Transcription Factors for the Targeted Therapy of Cancer (STAT3 Activators). 2009 Aug 27 [updated 2010 Dec 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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